发明授权
US07776877B2 N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
有权
N-（2-（杂芳基）芳基）芳基磺酰胺和N-（2-（芳基）芳基芳基磺酰胺
- 专利标题： N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
- 专利标题（中）： N-（2-（杂芳基）芳基）芳基磺酰胺和N-（2-（芳基）芳基芳基磺酰胺
-
申请号： US12140593申请日： 2008-06-17
-
公开(公告)号： US07776877B2公开(公告)日： 2010-08-17
- 发明人: Trevor T. Charvat , Cheng Hu , Anita Melikian , Aaron Novack , Andrew M. K. Pennell , Edward J. Sullivan , William D. Thomas , Solomon Ungashe , Penglie Zhang , Jay Powers , Sreenivas Punna
- 申请人： Trevor T. Charvat , Cheng Hu , Anita Melikian , Aaron Novack , Andrew M. K. Pennell , Edward J. Sullivan , William D. Thomas , Solomon Ungashe , Penglie Zhang , Jay Powers , Sreenivas Punna
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 代理机构： Brinks Hofer Gilson & Lione
- 主分类号： A01N43/42
- IPC分类号： A01N43/42 ; A61K31/44 ; C07D513/02 ; C07D515/02
摘要：
Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
公开/授权文献
信息查询
IPC分类:
