Invention Grant
US07781413B2 SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
有权
SEMA3B抑制肿瘤生长并诱导癌细胞凋亡
- Patent Title: SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
- Patent Title (中): SEMA3B抑制肿瘤生长并诱导癌细胞凋亡
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Application No.: US10285351Application Date: 2002-10-31
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Publication No.: US07781413B2Publication Date: 2010-08-24
- Inventor: John Minna , Yoshio Tomizawa , Yoshitaka Sekido , Michael Lerman
- Applicant: John Minna , Yoshio Tomizawa , Yoshitaka Sekido , Michael Lerman
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agency: Fulbright & Jaworski, LLP
- Main IPC: A61K31/713
- IPC: A61K31/713
Abstract:
The present invention identifies the semaphorin polypeptide SEMA3B as a tumor suppressor. This molecule can inhibit tumor growth and induce apoptosis of tumor cells when produced internally in a cancer cell via gene transfer, or when applied extracellularly. These observations permit new methods for treatment and diagnosis of cancer.
Public/Granted literature
- US20030166557A1 SEMA3B inhibits tumor growth and induces apoptosis in cancer cells Public/Granted day:2003-09-04
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