发明授权
US07790362B2 Controlled platelet activation to monitor therapy of ADP antagonists
有权
控制血小板活化以监测ADP拮抗剂的治疗
- 专利标题： Controlled platelet activation to monitor therapy of ADP antagonists
- 专利标题（中）： 控制血小板活化以监测ADP拮抗剂的治疗
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申请号： US10886155申请日： 2004-07-06
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公开(公告)号： US07790362B2公开(公告)日： 2010-09-07
- 发明人: Barry S. Coller , Dennis Durbin
- 申请人： Barry S. Coller , Dennis Durbin
- 申请人地址： US CA San Diego
- 专利权人： Accumetrics, Inc.
- 当前专利权人： Accumetrics, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Cooley, LLP
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00
摘要：
A method is provided of determining whether an individual has reduced ability to form platelet thrombi. An ADP platelet activator and one or platelet inhibitors are provided. At least one of the platelet inhibitors is Prostaglandin E1 (PGE1). An alternate signal transduction pathway is produced. A final concentration of ADP is 2 to 35 μM and a final concentration of PGE1 is 2 to 30 nM, preferably 20 to 25 nM.
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