发明授权
- 专利标题： Apparatus and method for piercing skin with microprotrusions
- 专利标题（中）： 用微刺穿皮肤的装置和方法
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申请号： US11092202申请日： 2005-03-28
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公开(公告)号： US07798987B2公开(公告)日： 2010-09-21
- 发明人: Joseph C. Trautman , Richard L. Keenan , Ahmad P. Samiee , WeiQi Lin , Michel J. N. Cormier , James A. Matriano , Peter E. Daddona
- 申请人： Joseph C. Trautman , Richard L. Keenan , Ahmad P. Samiee , WeiQi Lin , Michel J. N. Cormier , James A. Matriano , Peter E. Daddona
- 申请人地址： US CA Vacaville
- 专利权人： Alza Corporation
- 当前专利权人： Alza Corporation
- 当前专利权人地址： US CA Vacaville
- 代理机构： Edwards Angell Palmer & Dodge LLP
- 代理商 Kathleen Williams; Catherine J. Toppin
- 主分类号： A61B17/20
- IPC分类号： A61B17/20
摘要：
A method and device are described for applying a microprotrusion member (44) including a plurality of microprotrusions (90) to the stratum corneum with impact. The method and device are used to improve transport of an agent across the skin for agent delivery or sampling. The applicator (10, 60, 80) causes the microprotrusion member (44) to impact the stratum corneum with a certain amount of impact determined to effectively pierce the skin with the microprotrusions (90). The preferred applicator (10, 60, 80) impacts the stratum corneum with the microprotrusion member (44) with an impact of at least 0.05 joules per cm2 of the microprotrusion member (44) in 10 msec or less.