发明授权
- 专利标题: Microorganisms for the production of adipic acid and other compounds
- 专利标题(中): 用于生产己二酸等化合物的微生物
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申请号: US12413355申请日: 2009-03-27
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公开(公告)号: US07799545B2公开(公告)日: 2010-09-21
- 发明人: Anthony P. Burgard , Priti Pharkya , Robin E. Osterhout
- 申请人: Anthony P. Burgard , Priti Pharkya , Robin E. Osterhout
- 申请人地址: US CA San Diego
- 专利权人: Genomatica, Inc.
- 当前专利权人: Genomatica, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: McDermott Will & Emery LLP
- 主分类号: C12P7/40
- IPC分类号: C12P7/40 ; C12N1/20
摘要:
The invention provides a non-naturally occurring microbial organism having an adipate, 6-aminocaproic acid or caprolactam pathway. The microbial organism contains at least one exogenous nucleic acid encoding an enzyme in the respective adipate, 6-aminocaproic acid or caprolactam pathway. The invention additionally provides a method for producing adipate, 6-aminocaproic acid or caprolactam. The method can include culturing an adipate, 6-aminocaproic acid or caprolactam producing microbial organism, where the microbial organism expresses at least one exogenous nucleic acid encoding an adipate, 6-aminocaproic acid or caprolactam pathway enzyme in a sufficient amount to produce the respective product, under conditions and for a sufficient period of time to produce adipate, 6-aminocaproic acid or caprolactam.
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