发明授权
US07799806B2 Substituted n-benzyl piperidines as somatostatin receptor modulators
失效
取代的正丁基哌啶作为生长抑素受体调节剂
- 专利标题: Substituted n-benzyl piperidines as somatostatin receptor modulators
- 专利标题(中): 取代的正丁基哌啶作为生长抑素受体调节剂
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申请号: US12053781申请日: 2008-03-24
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公开(公告)号: US07799806B2公开(公告)日: 2010-09-21
- 发明人: Konrad Bleicher , Andreas D. Christ , Rainer E. Martin , Peter Mohr
- 申请人: Konrad Bleicher , Andreas D. Christ , Rainer E. Martin , Peter Mohr
- 申请人地址: US NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: US NJ Nutley
- 代理商 George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- 优先权: EP07105617 20070404
- 主分类号: A61K31/445
- IPC分类号: A61K31/445
摘要:
This invention relates to compounds of the formula wherein A, R1 to R3 are as defined in the claims and G is benzoimidazole, quinoxaline, benzotriazole, dihydro-imidazo[4,5-c]pyridinone and dihydro-isoindolone group as defined in the specification, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5 such as diabetes mellitus.
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