A universal support device for supporting a reconfigurable electronics device is disclosed. The universal support device includes an application specific integrated circuit (ASIC) module coupled to multiple non-volatile memory devices. The ASIC module is capable of interfacing with an external reconfigurable electronics device via a set of load/read-back interface lines and sense mitigation lines. The load/read-back interface lines are capable of being programmed to provide a parallel or a serial load and/or store protocols. The sense mitigation line can sense conditions that indicate a single-event functional interrupt or a radiation-induced event occurred within the reconfigurable electronics device.