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发明授权
US07807185B2 Methods of inhibiting growth of bacteria, yeast, fungus, and virus with Pseudomonas lindbergii and Bacillus coagulans extracellular products 有权
用Pseudomonas lindbergii和凝结芽孢杆菌细胞外产物抑制细菌，酵母，真菌和病毒生长的方法

Methods of inhibiting growth of bacteria, yeast, fungus, and virus with Pseudomonas lindbergii and Bacillus coagulans extracellular products
摘要：
The present invention discloses compositions derived from an isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain, suitable for topical application to the skin or mucosal membranes of a mammal, which are utilized to inhibit the growth of bacterium, yeast, fungi, virus, and combinations thereof. The present invention also discloses methods of treatment and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, by topical application of therapeutic compositions which are comprised, in part, of isolated Bacillus species, spores, or an extracellular product of Bacillus coagulans comprising a supernatant or filtrate of a culture of said Bacillus coagulans strain. In addition, the present invention also discloses compositions, methods of treatment, and therapeutic systems for inhibiting the growth of bacterium, yeast, fungi, virus, and combinations thereof, comprising an extracellular product of Pseudomonas lindbergii comprising a supernatant or filtrate of a culture of said Pseudomonas lindbergii strain.
摘要（中）：

本发明公开了衍生自分离的芽孢杆菌属物种，孢子或凝结芽孢杆菌的细胞外产物的组合物，其包含适于局部施用于哺乳动物皮肤或粘膜的所述凝结芽孢杆菌菌株的培养物的上清液或滤液， 用于抑制细菌，酵母，真菌，病毒及其组合的生长。 本发明还公开了通过局部施用治疗组合物来抑制细菌，酵母，真菌，病毒及其组合的生长的治疗方法和治疗系统，所述治疗组合物部分地由分离的芽孢杆菌属物种，孢子或 包含凝结芽孢杆菌菌株培养物的上清液或滤液的凝结芽孢杆菌的细胞外产物。 此外，本发明还公开了抑制细菌，酵母，真菌，病毒及其组合的生长的组合物，治疗方法和治疗系统，所述组合物包含嗜热假单胞菌（Pseudomonas lindbergii）的细胞外产物，其包含培养物的上清液或滤液 所述假丝酵母菌（Lseudomonas lindbergii）菌株。

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