发明授权
- 专利标题: Anti-viral pyrimidine nucleoside analogues
- 专利标题(中): 抗病毒嘧啶核苷类似物
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申请号: US10257855申请日: 2001-04-12
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公开(公告)号: US07820631B2公开(公告)日: 2010-10-26
- 发明人: Christopher McGuigan , Jan Balzarini
- 申请人: Christopher McGuigan , Jan Balzarini
- 申请人地址: BE Leuven GB Cardiff
- 专利权人: Rega Foundation,University College Cardiff Consultants Limited
- 当前专利权人: Rega Foundation,University College Cardiff Consultants Limited
- 当前专利权人地址: BE Leuven GB Cardiff
- 代理机构: Stites & Harbison PLLC
- 代理商 B. Aaron Schulman
- 优先权: GB0009486.2 20000417
- 国际申请: PCT/GB01/01694 WO 20010412
- 国际公布: WO01/83501 WO 20011108
- 主分类号: A61K31/7048
- IPC分类号: A61K31/7048 ; A61K31/7056 ; A61K31/7068 ; A61K31/519 ; A61K31/517 ; C07H19/06 ; C07H19/067 ; C07H19/073 ; C07H19/09 ; C07H19/10 ; C07H19/14 ; C07D491/048 ; C07D495/04 ; C07D239/70 ; C07C247/02
摘要:
A nucleoside analogue compound is provided which has a six-membered aromatic ring system, the aromatic ring system being substituted in the para position with an unbranched unsubstituted alkyl or alkoxy moiety, wherein the alkyl or alkoxy moiety, in total, has from 3 to 8 carbon atoms. This compound shows anti-vira1 activity, for example with respect to varicella zoster virus and can thus be used in therapeutic methods for the prophylaxis and treatment of viral infections such as varicella zoster virus.
公开/授权文献
- US20030148967A1 Anti-viral pyrimidine nucleoside analogues 公开/授权日:2003-08-07
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