发明授权
- 专利标题： Cellular telomerase vaccine and its use for treating cancer
- 专利标题（中）： 细胞端粒酶疫苗及其用于治疗癌症
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申请号： US11413838申请日： 2006-04-27
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公开(公告)号： US07824849B2公开(公告)日： 2010-11-02
- 发明人: Federico C. A. Gaeta
- 申请人： Federico C. A. Gaeta
- 申请人地址： US CA Menlo Park
- 专利权人： Geron Corporation
- 当前专利权人： Geron Corporation
- 当前专利权人地址： US CA Menlo Park
- 代理商 David J. Earp; Leslie A. Mool
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00
摘要：
The invention provides dendritic cell (DC) preparations that present a telomerase reverse transcriptase (TRT) peptide in the context of an MHC class I or MHC class II molecule. The DCs may be pulsed with a TRT polypeptide, or may comprise a recombinant polynucleotide encoding TRT. The invention also describes the use of such compositions for the prevention and treatment of cancers and other diseases.
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