Invention Grant
US07825115B2 Cyclic urea compounds, preparation thereof and pharmaceutical use thereof as kinase inhibitors
失效
环状尿素化合物，其制备及其作为激酶抑制剂的药物用途
- Patent Title: Cyclic urea compounds, preparation thereof and pharmaceutical use thereof as kinase inhibitors
- Patent Title (中): 环状尿素化合物，其制备及其作为激酶抑制剂的药物用途
-
Application No.: US11972314Application Date: 2008-01-10
-
Publication No.: US07825115B2Publication Date: 2010-11-02
- Inventor: Marcel Patek , Anil Nair , Augustin Hittinger , Conception Nemecek , Daniel Bond , Greg Harlow , Herve Bouchard , Jacques Mauger , Jean-Luc Malleron , Mark Palermo , Fahad Al-Obeidi , Thomas Faitg , Hartmut Strobel , Sven Ruf , Kurt Ritter , Youssef El-Ahmad , Dominique Lesuisse , Didier Bénard
- Applicant: Marcel Patek , Anil Nair , Augustin Hittinger , Conception Nemecek , Daniel Bond , Greg Harlow , Herve Bouchard , Jacques Mauger , Jean-Luc Malleron , Mark Palermo , Fahad Al-Obeidi , Thomas Faitg , Hartmut Strobel , Sven Ruf , Kurt Ritter , Youssef El-Ahmad , Dominique Lesuisse , Didier Bénard
- Applicant Address: FR Antony
- Assignee: Aventis Pharma S.A.
- Current Assignee: Aventis Pharma S.A.
- Current Assignee Address: FR Antony
- Agent Kelly L. Bender
- Priority: FR0301098 20030131
- Main IPC: C07D401/06
- IPC: C07D401/06 ; C07D403/06 ; A61K31/41
Abstract:
The disclosure relates to a cyclic urea compound of formula I: as defined herein, to the process for its preparation, pharmaceutical composition comprising it and its pharmaceutical use as an inhibitor on a protein kinase. Thus, the compound of formula I is useful for preventing or treating a physiological disorder capable of being modulated by inhibiting the activity of a protein kinase, such as a solid tumor.
Public/Granted literature
- US20080108654A1 Cyclic Urea Compounds, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors Public/Granted day:2008-05-08
Information query
