发明授权
- 专利标题： Circulating mRNA as diagnostic markers
- 专利标题（中）： 循环mRNA作为诊断标记
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申请号： US11807258申请日： 2007-05-24
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公开(公告)号： US07829285B2公开(公告)日： 2010-11-09
- 发明人: Yuk-Ming Dennis Lo , Kai On Ng , Bo Yin Tsui , Wai Kwun Rossa Chiu
- 申请人： Yuk-Ming Dennis Lo , Kai On Ng , Bo Yin Tsui , Wai Kwun Rossa Chiu
- 申请人地址： HK Shatin, New Territories, SAR
- 专利权人： The Chinese University of Hong Kong
- 当前专利权人： The Chinese University of Hong Kong
- 当前专利权人地址： HK Shatin, New Territories, SAR
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
摘要：
Methods and kits are provided for diagnosing, monitoring, or predicting the conditions of pre-eclampsia, fetal chromosomal aneuploidy, and pre-term labor in a pregnant woman, as well as for detecting pregnancy in a woman, by quantitatively measuring in the maternal blood the amount of one or more mRNA species encoding human chorionic gonadotropin β subunit (hCG-β), human placental lactogen (hPL), human corticotropin releasing hormone (hCRH), KiSS-1 metastasis-suppressor (KISS1), tissue factor pathway inhibitor 2 (TPFI2), placenta-specific 1 (PLAC1), or glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and comparing the amount of the mRNA species with a standard control.
公开/授权文献
- US20090162842A1 Circulating mRNA as diagnostic markers 公开/授权日：2009-06-25
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