发明授权
US07834017B2 Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
有权
含二胺的四取代哌嗪化合物具有相同的1-取代基和4-取代基
- 专利标题： Diamine-containing, tetra-substituted piperazine compounds having identical 1- and 4-substituents
- 专利标题（中）： 含二胺的四取代哌嗪化合物具有相同的1-取代基和4-取代基
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申请号： US11836897申请日： 2007-08-10
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公开(公告)号： US07834017B2公开(公告)日： 2010-11-16
- 发明人: Kevin Burris , Yi-Qun Shi , Shubh D. Sharma , Yadi Reddy Bonuga , Papireddy Purma
- 申请人： Kevin Burris , Yi-Qun Shi , Shubh D. Sharma , Yadi Reddy Bonuga , Papireddy Purma
- 申请人地址： US NJ Cranbury
- 专利权人： Palatin Technologies, Inc.
- 当前专利权人： Palatin Technologies, Inc.
- 当前专利权人地址： US NJ Cranbury
- 代理商 Stephen A. Slusher
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; C07D403/00 ; C07D295/00
摘要：
There is provided compounds having the formula of structure I: wherein the groups —C(R8)(CH2)vCH(R9)(CH2)y-Q and —C(R8)(CH2)vCH(R9)(CH2)y-J are the same, and R1a, R1b, R2a, R2b, R8, R9, J, Q, W, X, L2, v and y have meanings given in the description. The use of such compounds in the treatment of a condition responsive to changes in melanocortin receptor function in a human or non-human mammal (e.g. male sexual dysfunction, female sexual dysfunction, an eating disorder, above optimal body weight, obesity, below-optimal body weight or cachexia) is also described.