A distributed detector system is provided for remotely detecting agents indicating the presence of particular biological, explosive, or chemical targets. The distributed detector system may be used for security threat detection, manufacturing or environmental monitoring, or medical assaying. In the detection system, a central server or base station wirelessly communicates with a set of distributed detectors. In this way, the central server or base station is able to aggregate detection information, as well as apply additional processing and analysis to data collected at the detectors. Each detector has a reactive material, such as a silicon-polymer, that changes an optical property in the presence of a target agent. A camera is positioned to take images of the reactive material from time to time, and has local processing to determine when the reactive material has likely changed. In some cases, the detector may have sufficient processing power to classify the change according to its urgency or threat level. The detector wirelessly communications to the central server or base station, and appropriate alerts or notifications can be generated.