Invention Grant
- Patent Title: Antisense modulation of BCL2-associated X protein expression
- Patent Title (中): BCL2相关X蛋白表达的反义调制
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Application No.: US10728509Application Date: 2003-12-05
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Publication No.: US07846730B2Publication Date: 2010-12-07
- Inventor: Hong Zhang , Andrew T. Watt
- Applicant: Hong Zhang , Andrew T. Watt
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc.-Patent Dept. Knobbe Martens Olson & Bear LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C12N15/88 ; C07H21/02 ; C07H21/04
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of BCL2-associated X protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding BCL2-associated X protein. Methods of using these compounds for modulation of BCL2-associated X protein expression and for treatment of diseases associated with expression of BCL2-associated X protein are provided.
Public/Granted literature
- US20040077583A1 Antisense modulation of BCL2-associated X protein expression Public/Granted day:2004-04-22
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