发明授权
- 专利标题: Compositions and methods for detecting cancer
- 专利标题(中): 组成和检测癌症的方法
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申请号: US11840112申请日: 2007-08-16
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公开(公告)号: US07851144B2公开(公告)日: 2010-12-14
- 发明人: Teresa A. Brentnall , Ru Chen , Katherine L. Pogue-Geile , David C. Whitcomb , Mary Patricia Bronner , Carol A. Otey
- 申请人: Teresa A. Brentnall , Ru Chen , Katherine L. Pogue-Geile , David C. Whitcomb , Mary Patricia Bronner , Carol A. Otey
- 申请人地址: US WA Seattle US NC Chapel Hill US PA Pittsburgh US OH Cleveland
- 专利权人: The University of Washington,The University of North Carolina at Chapel Hill,The University of Pittsburgh,The Cleveland Clinic Foundation
- 当前专利权人: The University of Washington,The University of North Carolina at Chapel Hill,The University of Pittsburgh,The Cleveland Clinic Foundation
- 当前专利权人地址: US WA Seattle US NC Chapel Hill US PA Pittsburgh US OH Cleveland
- 代理机构: canady + lortz LLP
- 代理商 Karen S. Canady
- 主分类号: C12Q1/00
- IPC分类号: C12Q1/00 ; G01N33/574
摘要:
The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
公开/授权文献
- US20080318225A1 COMPOSITIONS AND METHODS FOR DETECTING CANCER 公开/授权日:2008-12-25