- 专利标题: Biphenyl compounds useful as muscarinic receptor antagonists
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申请号: US11879829申请日: 2007-07-19
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公开(公告)号: US07851631B2公开(公告)日: 2010-12-14
- 发明人: Mathai Mammen , Yu-Hua Ji , YongQi Mu , Eric L. Stangeland , Aaron Kushner , Craig Husfeld
- 申请人: Mathai Mammen , Yu-Hua Ji , YongQi Mu , Eric L. Stangeland , Aaron Kushner , Craig Husfeld
- 申请人地址: US CA South San Francisco
- 专利权人: Theravance, Inc.
- 当前专利权人: Theravance, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理商 Jeffrey A. Hagenah; Shelley Eberle
- 主分类号: C07D401/12
- IPC分类号: C07D401/12 ; A61K31/454
摘要:
This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, r, R1, R2, R3, R4, R5, R6, R7, and W are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders.
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