Invention Grant
- Patent Title: Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser
- Patent Title (中): 使用微磁珠和激光快速破坏细胞或病毒的方法和装置
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Application No.: US11253541Application Date: 2005-10-19
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Publication No.: US07855069B2Publication Date: 2010-12-21
- Inventor: Jeong-gun Lee , Young-nam Kwon , Young-a Kim , Myo-yong Lee , Shin-i Yoo , Yeon-ja Cho , Kwang-ho Cheong , Chang-eun Yoo , Seung-yeon Yang
- Applicant: Jeong-gun Lee , Young-nam Kwon , Young-a Kim , Myo-yong Lee , Shin-i Yoo , Yeon-ja Cho , Kwang-ho Cheong , Chang-eun Yoo , Seung-yeon Yang
- Applicant Address: KR
- Assignee: Samsung Electronics Co., Ltd.
- Current Assignee: Samsung Electronics Co., Ltd.
- Current Assignee Address: KR
- Agency: Cantor Colburn LLP
- Priority: KR10-2004-0083586 20041019; KR10-2005-0038988 20050510; KR10-2005-0078886 20050826
- Main IPC: C12M1/42
- IPC: C12M1/42 ; C12M1/33

Abstract:
A method and apparatus for a rapid disruption of cells or viruses using micro magnetic beads and a laser are provided. According to the method and apparatus for a rapid disruption of cells or viruses using micro magnetic beads and a laser, cell lysis within 40 seconds is possible, the apparatus can be miniaturized using a laser diode, a DNA purification step can be directly performed after a disruption of cells or viruses, and a solution containing DNA can be transferred to a subsequent step after cell debris and beads to which inhibitors of a subsequent reaction are attached are removed with an electromagnet. In addition, by means of the cell lysis chip, an evaporation problem is solved, vibrations can be efficiently transferred to cells through magnetic beads, a microfluidics problem on a rough surface is solved by hydrophobically treating the inner surface of the chip, and the cell lysis chip can be applied to LOC.
Public/Granted literature
- US20060084165A1 Method and apparatus for the rapid disruption of cells or viruses using micro magnetic beads and laser Public/Granted day:2006-04-20
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