发明授权
US07855076B2 Use of discoidin domain receptor 1 (DDR1) and agents that affect the DDR1/collagen pathway
失效
使用盘状结构域受体1（DDR1）和影响DDR1 /胶原途径的试剂
- 专利标题： Use of discoidin domain receptor 1 (DDR1) and agents that affect the DDR1/collagen pathway
- 专利标题（中）： 使用盘状结构域受体1（DDR1）和影响DDR1 /胶原途径的试剂
-
申请号： US10507385申请日： 2002-12-11
-
公开(公告)号： US07855076B2公开(公告)日： 2010-12-21
- 发明人: Teizo Yoshimura , Hidenobu Kamohara
- 申请人： Teizo Yoshimura , Hidenobu Kamohara
- 申请人地址： US DC Washington
- 专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人： The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Klarquist Sparkman, LLP.
- 国际申请： PCT/US02/39793 WO 20021211
- 国际公布： WO03/082328 WO 20031009
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/02
摘要：
The disclosure provides methods of modulating the activity of DDR1. Methods for screening for agents that activate DDR1 are disclosed. Methods for inducing the maturation of immature macrophages and immature dendritic cells are also disclosed. In addition, methods for increasing neutrophil activation using a DDR1 activating agent, and methods for increasing leukocyte migration using a DDR1 activating agent, are provided.
公开/授权文献
信息查询
