发明授权
- 专利标题: Benzamide derivative or salt thereof
- 专利标题(中): 苯甲酰胺衍生物或其盐
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申请号: US12496993申请日: 2009-07-02
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公开(公告)号: US07855198B2公开(公告)日: 2010-12-21
- 发明人: Takahiro Kuramochi , Norio Asai , Kazuhiro Ikegai , Seijiro Akamatsu , Hironori Harada , Noriko Ishikawa , Shohei Shirakami , Satoshi Miyamoto , Toshihiro Watanabe , Tetsuo Kiso
- 申请人: Takahiro Kuramochi , Norio Asai , Kazuhiro Ikegai , Seijiro Akamatsu , Hironori Harada , Noriko Ishikawa , Shohei Shirakami , Satoshi Miyamoto , Toshihiro Watanabe , Tetsuo Kiso
- 申请人地址: JP Tokyo
- 专利权人: Astellas Pharma Inc.
- 当前专利权人: Astellas Pharma Inc.
- 当前专利权人地址: JP Tokyo
- 代理机构: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 优先权: JP2003-167865 20030612; JP2003-405086 20031203
- 主分类号: C07D413/10
- IPC分类号: C07D413/10 ; C07D413/14 ; A61K31/538
摘要:
There is provided a compound having a capsaicin receptor VR1 inhibitory activity and useful as a therapeutic agent for various pains including inflammatory pain and neurogenic pain, migraine, cluster headache, bladder diseases including overactive bladder, and the like.A benzamide derivative or a salt thereof wherein a benzene ring is attached to a D ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring) through an amide bond, the benzene ring is directly bonded to an E ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring), and the benzene ring is further bonded to A (an amino moiety, a monocyclic or bicyclic heterocycle) through L (a lower alkylene).
公开/授权文献
- US20090270365A1 BENZAMIDE DERIVATIVE OR SALT THEREOF 公开/授权日:2009-10-29