发明授权
US07855214B2 Fused cyclic systems useful as inhibitors of TEC family protein kinases
有权
融合的循环系统可用作TEC家族蛋白激酶的抑制剂
- 专利标题: Fused cyclic systems useful as inhibitors of TEC family protein kinases
- 专利标题(中): 融合的循环系统可用作TEC家族蛋白激酶的抑制剂
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申请号: US11046664申请日: 2005-01-26
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公开(公告)号: US07855214B2公开(公告)日: 2010-12-21
- 发明人: Juan-Miguel Jimenez , Sanjay Patel , David Kay , Ronald Knegtel , Oliver Philps
- 申请人: Juan-Miguel Jimenez , Sanjay Patel , David Kay , Ronald Knegtel , Oliver Philps
- 申请人地址: US MA Cambridge
- 专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人: Vertex Pharmaceuticals Incorporated
- 当前专利权人地址: US MA Cambridge
- 代理商 Jennifer G. Che
- 主分类号: C07D487/22
- IPC分类号: C07D487/22 ; C07D487/14 ; A61K31/519 ; A61P35/00 ; A61P29/00
摘要:
The present invention relates to compounds useful as inhibitors of Tec family protein kinases. These compounds have the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, G, Cy1, and X are as defined herein. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.
公开/授权文献
- US20050209255A1 Compositions useful as inhibitors of protein kinases 公开/授权日:2005-09-22