Invention Grant
US07855308B2 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
有权
11-β-羟基类固醇脱氢酶1型酶的抑制剂
- Patent Title: Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
- Patent Title (中): 11-β-羟基类固醇脱氢酶1型酶的抑制剂
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Application No.: US12355909Application Date: 2009-01-19
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Publication No.: US07855308B2Publication Date: 2010-12-21
- Inventor: Michael E. Brune , Peer B. Jacobson , James T. Link , Jyoti R. Patel , Jeffrey J. Rohde , Qi Shuai , Martin Winn , Vince S. Yeh , Hong Yong
- Applicant: Michael E. Brune , Peer B. Jacobson , James T. Link , Jyoti R. Patel , Jeffrey J. Rohde , Qi Shuai , Martin Winn , Vince S. Yeh , Hong Yong
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Sreenivasarao Vepachedu
- Main IPC: C07C233/05
- IPC: C07C233/05 ; A61K31/65
Abstract:
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome and other diseases and conditions that are mediated by excessive glucocorticoid action.
Public/Granted literature
- US20090131434A1 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme Public/Granted day:2009-05-21
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