发明授权
- 专利标题: Inhibition of phosphoinositide 3-kinase β
- 专利标题(中): 磷酸肌醇3激酶和bgr的抑制作用
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申请号: US11964842申请日: 2007-12-27
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公开(公告)号: US07872011B2公开(公告)日: 2011-01-18
- 发明人: Shaun P. Jackson , Alan D. Robertson , Vijaya Kenche , Philip Thompson , Hishani Prabaharan , Karen Anderson , Belinda Abbott , Isaac Goncalves , Warwick Nesbitt , Simone Shoenwaelder , Dilek Saylik
- 申请人: Shaun P. Jackson , Alan D. Robertson , Vijaya Kenche , Philip Thompson , Hishani Prabaharan , Karen Anderson , Belinda Abbott , Isaac Goncalves , Warwick Nesbitt , Simone Shoenwaelder , Dilek Saylik
- 申请人地址: SE Sodertalje
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 当前专利权人地址: SE Sodertalje
- 代理机构: Pepper Hamilton LLP
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; A61K31/4709 ; A61K31/443 ; C07D401/04 ; C07D405/04 ; C07D471/04
摘要:
The present invention relates to selective inhibitors of phosphoinositide (PI) 3-kinase β, use of the selective inhibitors in anti-thrombotic therapy, and a method for screening compounds useful for the new anti-thrombotic therapy by detecting selective inhibitory activity of PI 3-kinase β of the compound. The invention also relates to novel compounds that are inhibitors of PI 3-kinase.
公开/授权文献
- US20080319021A1 Inhibition Of Phosphoinositide 3-Kinase Beta 公开/授权日:2008-12-25
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