发明授权
- 专利标题： Crystalline antifungal compounds
- 专利标题（中）： 结晶抗真菌化合物
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申请号： US11882892申请日： 2007-08-06
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公开(公告)号： US07879867B2公开(公告)日： 2011-02-01
- 发明人: Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- 申请人： Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- 申请人地址： ES Palau-solita i Plegamans US FL Coral Gables
- 专利权人： Palau Pharma, S.A.,Stiefel Laboratories, Inc.
- 当前专利权人： Palau Pharma, S.A.,Stiefel Laboratories, Inc.
- 当前专利权人地址： ES Palau-solita i Plegamans US FL Coral Gables
- 代理商 Gary M. Nath; Joshua B. Goldberg; Charles D. Niebylski
- 优先权： EP06380225 20060807; EP07380186 20070626
- 主分类号： A61K31/517
- IPC分类号： A61K31/517
摘要：
Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2 -(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin -4(3H)-one, represented by formula II:
公开/授权文献
- US20080076787A1 Crystalline antifungal compounds 公开/授权日：2008-03-27
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