An active flow control (AFC) system for use with a wind turbine is provided. The wind turbine includes at least one rotor blade having at least one manifold extending at least partially therethrough and at least one aperture defined through a surface of the at least one rotor blade. The at least one aperture is in flow communication with the at least one manifold. The AFC system includes an air intake duct configured to draw ambient air into the wind turbine, a self-cleaning air filter coupled in flow communication with the air intake duct and configured to filter the ambient air, and an AFC distribution system configured to eject the filtered air through the at least one aperture.