- 专利标题: Compounds for the treatment of proliferative disorders
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申请号: US11355922申请日: 2006-02-16
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公开(公告)号: US07884094B2公开(公告)日: 2011-02-08
- 发明人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- 申请人地址: US MA Lexington
- 专利权人: Synta Pharmaceuticals Corp.
- 当前专利权人: Synta Pharmaceuticals Corp.
- 当前专利权人地址: US MA Lexington
- 代理机构: Foley & Lardner LLP
- 代理商 Steven G. Davis
- 主分类号: A61K31/33
- IPC分类号: A61K31/33 ; C07D261/02
摘要:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
公开/授权文献
- US20060217389A1 Compounds for the treatment of proliferative disorders 公开/授权日:2006-09-28
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