发明授权
- 专利标题： Antisense modulation of apolipoprotein B expression
- 专利标题（中）： 载脂蛋白B表达的反义调节
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申请号： US09920033申请日： 2001-08-01
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公开(公告)号： US07888324B2公开(公告)日： 2011-02-15
- 发明人: Rosanne M. Crooke , Mark J. Graham
- 申请人： Rosanne M. Crooke , Mark J. Graham
- 申请人地址： US MA Cambridge
- 专利权人： Genzyme Corporation
- 当前专利权人： Genzyme Corporation
- 当前专利权人地址： US MA Cambridge
- 代理机构： Jones Day
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H21/04
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of apolipoprotein B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding apolipoprotein B. Methods of using these compounds for modulation of apolipoprotein B expression and for treatment of diseases associated with expression of apolipoprotein B are provided.
公开/授权文献
- US20030087853A1 Antisense modulation of apolipoprotein B expression 公开/授权日：2003-05-08
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