- 专利标题： Degradable clostridial toxins
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申请号： US11572512申请日： 2005-09-01
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公开(公告)号： US07892565B2公开(公告)日： 2011-02-22
- 发明人: Lance E. Steward , Ester G. Fernandez-Salas , Marcella A. Gilmore , Joseph Francis , Shengwen Li , Kei Roger Aoki
- 申请人： Lance E. Steward , Ester G. Fernandez-Salas , Marcella A. Gilmore , Joseph Francis , Shengwen Li , Kei Roger Aoki
- 申请人地址： US CA Irvine
- 专利权人： Allergan, Inc.
- 当前专利权人： Allergan, Inc.
- 当前专利权人地址： US CA Irvine
- 代理商 Kenton Abel; Debra Condino; Dean Stathakis
- 国际申请： PCT/US2005/031613 WO 20050901
- 国际公布： WO2006/026780 WO 20060309
- 主分类号： C07K1/00
- IPC分类号： C07K1/00 ; C07K14/00 ; C07H21/02
摘要：
The specification discloses modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; polynucleotide molecules encoding modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain; and method of producing modified Clostridial toxins comprising a PAR ligand domain, a Clostridial toxin enzymatic domain, a Clostridial toxin translocation domain and a Clostridial toxin binding domain.
公开/授权文献
- US20080213830A1 Degradable Clostridial Toxins 公开/授权日：2008-09-04
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