发明授权
US07893048B2 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
失效
2-氮杂环丁酮衍生物作为治疗高脂血症的胆固醇吸收抑制剂
- 专利标题: 2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions
- 专利标题(中): 2-氮杂环丁酮衍生物作为治疗高脂血症的胆固醇吸收抑制剂
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申请号: US11993466申请日: 2006-06-21
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公开(公告)号: US07893048B2公开(公告)日: 2011-02-22
- 发明人: Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ingemar Starke
- 申请人: Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ingemar Starke
- 申请人地址: SE Sodertalje
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 当前专利权人地址: SE Sodertalje
- 代理机构: Pepper Hamilton LLP
- 优先权: SE0501465 20050622
- 国际申请: PCT/SE2006/000765 WO 20060621
- 国际公布: WO2006/137796 WO 20061228
- 主分类号: C07D205/08
- IPC分类号: C07D205/08 ; C07D405/12 ; A61K31/397 ; A61P3/06 ; A61P9/10 ; C07D319/06 ; C07D413/14
摘要:
Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
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