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1.发明申请Novel 2-Azetidinone Derivatives And Their Use As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemia 失效新型2-氮杂环丁酮衍生物及其用作治疗高脂血症的胆固醇吸收抑制剂公开(公告)号：US20100216759A1
公开(公告)日：2010-08-26
申请号：US11993033
申请日：2006-06-19
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
IPC分类号： A61K31/397 , C07D205/04 , A61P9/00
CPC分类号： C07D205/08 , C07K5/06026
摘要： Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述了式（I）化合物（其中可变基团如本文所定义）药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药，以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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2.发明授权2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions 失效2-氮杂环丁酮衍生物作为治疗高脂血症的胆固醇吸收抑制剂公开(公告)号：US07893048B2
公开(公告)日：2011-02-22
申请号：US11993466
申请日：2006-06-21
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ingemar Starke
IPC分类号： C07D205/08 , C07D405/12 , A61K31/397 , A61P3/06 , A61P9/10 , C07D319/06 , C07D413/14
CPC分类号： C07D205/08 , C07D405/12 , C07D405/14 , C07K5/06026
摘要： Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述式（I）的化合物（其中可变基团如本文所定义）其药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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3.发明申请Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitory Activity 失效具有胆固醇吸收抑制活性的二苯基氮杂环丁酮衍生物公开(公告)号：US20100099657A2
公开(公告)日：2010-04-22
申请号：US10596731
申请日：2006-11-16
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
IPC分类号： A61K31/397 , A61K31/4025 , A61K31/405 , A61P25/28 , A61P3/06 , A61P35/00 , A61P9/10 , C07D205/04 , C07D403/02
CPC分类号： C07D205/08 , A61K38/00 , C07K5/06026 , C07K5/06078
摘要： Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述了式（I）化合物（其中可变基团如本文所定义）药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药，以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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4.发明申请Diphenylazetidinone Derivatives Possessing Cholesterol Absorption Inhibitory Activity 失效具有胆固醇吸收抑制活性的二苯基氮杂环丁酮衍生物公开(公告)号：US20080064676A1
公开(公告)日：2008-03-13
申请号：US10596731
申请日：2004-12-21
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
IPC分类号： A61K31/397 , A61K31/4025 , A61K31/405 , A61P25/28 , A61P3/06 , A61P35/00 , A61P9/10 , C07D205/04 , C07D403/02
CPC分类号： C07D205/08 , A61K38/00 , C07K5/06026 , C07K5/06078
摘要： Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述了式（I）化合物（其中可变基团在其中定义）药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药，以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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5.发明申请Novel 2-Azetidinone Derivatives As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemic Conditions 失效新型2-氮杂环丁酮衍生物作为胆固醇吸收抑制剂治疗高脂血症公开(公告)号：US20100137273A1
公开(公告)日：2010-06-03
申请号：US11993466
申请日：2006-06-21
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ingemar Starke
IPC分类号： A61K31/397 , C07D405/10 , C07D205/09 , A61P3/00 , A61P9/10 , A61P25/28
CPC分类号： C07D205/08 , C07D405/12 , C07D405/14 , C07K5/06026
摘要： Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述式（I）的化合物（其中可变基团如本文所定义）其药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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6.发明申请Diphenylazetidinone derivatives possessing chloesterol absorption inhibitory activity 审中-公开具有氯黄酮吸收抑制活性的二苯基氮杂环丁酮衍生物公开(公告)号：US20070142304A1
公开(公告)日：2007-06-21
申请号：US10596725
申请日：2004-12-21
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
CPC分类号： C07D205/08
摘要： Compounds of formula (XV): [Chemical formula should be inserted here. Please see paper copy] (XV) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 式（XV）化合物：[化学式应在此插入。 描述了可药用盐，溶剂合物，这些盐及其前药的溶剂化物及其作为治疗高脂血症的胆固醇吸收抑制剂的用途的文献（XV）（XV）（其中可变基团在其中定义）。 还描述了其制备方法和含有它们的药物组合物。
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7.发明授权2-azetidinone derivatives and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia 失效2-氮杂环丁酮衍生物及其作为治疗高脂血症的胆固醇吸收抑制剂的用途公开(公告)号：US07863265B2
公开(公告)日：2011-01-04
申请号：US11993033
申请日：2006-06-19
申请人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlstrom , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjaret , Ingemar Starke
IPC分类号： A61K31/397 , C07D205/08 , C07D413/12 , C07D319/06 , A61P3/06
CPC分类号： C07D205/08 , C07K5/06026
摘要： Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述了式（I）化合物（其中可变基团如本文所定义）药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药，以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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8.发明授权Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity 失效具有胆固醇吸收抑制活性的二苯基氮杂环丁酮衍生物公开(公告)号：US07871998B2
公开(公告)日：2011-01-18
申请号：US10596731
申请日：2004-12-21
申请人： Susanne Alenfalk , Mikael Dahlström , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjäret , Ingemar Starke
发明人： Susanne Alenfalk , Mikael Dahlström , Fana Hunegnaw , Staffan Karlsson , Malin Lemurell , Ann-Margret Lindqvist , Tore Skjäret , Ingemar Starke
IPC分类号： C07D205/08 , A61K31/397 , A61P31/10 , A61P25/28 , A61P3/10
CPC分类号： C07D205/08 , A61K38/00 , C07K5/06026 , C07K5/06078
摘要： Compounds of formula (I): (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述式（I）的化合物（其中可变基团如本文所定义）其药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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9.发明授权2-azetidinone derivatives as cholesterol absorption inhibitors for the treatment of hyperlipidaemic conditions 失效2-氮杂环丁酮衍生物作为治疗高脂血症的胆固醇吸收抑制剂公开(公告)号：US07906502B2
公开(公告)日：2011-03-15
申请号：US11993463
申请日：2006-06-21
IPC分类号： C07D205/08 , C07D405/12 , A61K31/397 , A61P3/06 , A61P9/10 , C07D319/06 , C07D413/14
CPC分类号： C07D405/12
摘要： Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述了式（I）化合物（其中可变基团如本文所定义）药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药，以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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10.发明申请Novel 2-Azetidinone Derivatives As Cholesterol Absorption Inhibitors For The Treatment Of Hyperlipidaemic Conditions 失效新型2-氮杂环丁酮衍生物作为胆固醇吸收抑制剂治疗高脂血症公开(公告)号：US20100168039A1
公开(公告)日：2010-07-01
申请号：US11993463
申请日：2006-06-21
CPC分类号： C07D405/12
摘要： Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.
摘要翻译： 描述了式（I）化合物（其中可变基团如本文所定义）药学上可接受的盐，溶剂合物，这些盐的溶剂合物和前药，以及它们作为用于治疗高脂血症的胆固醇吸收抑制剂的用途。 还描述了其制备方法和含有它们的药物组合物。
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