发明授权
- 专利标题： Magnetic beads comprising an outer coating of hydrophilic porous polymer and method of making thereof
- 专利标题（中）： 包含亲水性多孔聚合物的外涂层的磁珠及其制造方法
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申请号： US11911540申请日： 2006-04-13
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公开(公告)号： US07897257B2公开(公告)日： 2011-03-01
- 发明人: Mathias Alterman , Andreas Axen , Gunnar Glad , Dag Lindstrom , Ulrika Meyer , Nils Norrman , Tobias Soderman
- 申请人： Mathias Alterman , Andreas Axen , Gunnar Glad , Dag Lindstrom , Ulrika Meyer , Nils Norrman , Tobias Soderman
- 申请人地址： SE Uppsala
- 专利权人： GE Healthcare Bio-Sciences AB
- 当前专利权人： GE Healthcare Bio-Sciences AB
- 当前专利权人地址： SE Uppsala
- 代理商 Yonggang Ji
- 优先权： SE0500870 20050418
- 国际申请： PCT/SE2006/000439 WO 20060413
- 国际公布： WO2006/112771 WO 20061026
- 主分类号： B32B5/16
- IPC分类号： B32B5/16 ; B05D7/00
摘要：
The present invention relates to magnetic beads suitable for, for example, isolation of proteins, cells, and viruses and also for diagnostic applications and cell cultivation. The magnetic beads are composite beads with an inner core of metal particles, which are coated with an inert synthetic polymer and these are then enclosed in a hydrophilic porous polymer, preferably agarose. This provides porous biocompatible beads without metal leakage. The beads may be used for cell cultivation or for chromatography. When the beads are used for chromatography the agarose layer is preferably provided with ligands having affinity for selected biomolecules.
公开/授权文献
- US20080152939A1 Magnetic Beads 公开/授权日：2008-06-26
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