发明授权
US07906635B2 Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer
有权
核苷酸和氨基酸序列，以及其用于诊断卵巢癌的测定和方法
- 专利标题： Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of ovarian cancer
- 专利标题（中）： 核苷酸和氨基酸序列，以及其用于诊断卵巢癌的测定和方法
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申请号： US12354641申请日： 2009-01-15
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公开(公告)号： US07906635B2公开(公告)日： 2011-03-15
- 发明人: Gad S. Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
- 申请人： Gad S. Cojocaru , Sarah Pollock , Zurit Levine , Alexander Diber , Guy Kol , Amir Toporik , Rotem Sorek , Dvir Dahary , Michal Ayalon-Soffer , Pinchas Akiva , Amit Novik , Yossi Cohen , Osnat Sella-Tavor , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Maxim Shklar
- 申请人地址： IL Tel Aviv
- 专利权人： Compugen Ltd.
- 当前专利权人： Compugen Ltd.
- 当前专利权人地址： IL Tel Aviv
- 代理机构： Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi; David E. Johnson, Esq.
- 主分类号： C07H21/02
- IPC分类号： C07H21/02 ; C12Q1/68
摘要：
Novel markers for ovarian cancer that are both sensitive and accurate. These markers are overexpressed and/or differentially expressed in ovarian cancer specifically, as opposed to normal ovarian tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis, in ovarian cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between ovarian cancer and non-cancerous states.
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