发明授权
- 专利标题: Antibodies to VLA-1
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申请号: US12727965申请日: 2010-03-19
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公开(公告)号: US07910099B2公开(公告)日: 2011-03-22
- 发明人: Michael Karpusas , Paul D. Lyne , Jose William Saldanha , Ellen A. Garber
- 申请人: Michael Karpusas , Paul D. Lyne , Jose William Saldanha , Ellen A. Garber
- 申请人地址: US MA Cambridge
- 专利权人: Biogen Idec MA Inc.
- 当前专利权人: Biogen Idec MA Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Lando & Anastasi, LLP
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.
公开/授权文献
- US20100272716A1 Antibodies to VLA-1 公开/授权日:2010-10-28
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