发明授权
US07910305B2 Methods for screening for compounds that modulate insulin promoter activity
有权
筛选调节胰岛素启动子活性的化合物的方法
- 专利标题： Methods for screening for compounds that modulate insulin promoter activity
- 专利标题（中）： 筛选调节胰岛素启动子活性的化合物的方法
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申请号： US11992028申请日： 2006-09-14
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公开(公告)号： US07910305B2公开(公告)日： 2011-03-22
- 发明人: Mark Mercola , Fred Levin , Pamela Itkin-Ansari
- 申请人： Mark Mercola , Fred Levin , Pamela Itkin-Ansari
- 申请人地址： US CA La Jolla
- 专利权人： The Burnham Institute for Medical Research
- 当前专利权人： The Burnham Institute for Medical Research
- 当前专利权人地址： US CA La Jolla
- 代理机构： TechLaw LLP
- 代理商 Sam K. Tahmassebi
- 国际申请： PCT/US2006/036133 WO 20060914
- 国际公布： WO2007/035546 WO 20070329
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
Compositions and methods are provided for screening for compounds that modulate insulin promoter activity. Vectors that express green fluorescent protein under the control of the human insulin promoter are introduced into mouse and human cells in which the insulin promoter is expressed in a glucose-responsive manner. Such cells are then used to screen for compounds that modulate insulin promoter activity.
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