Disclosed is an integrated multi-measurement system for measuring physical properties including thickness, electrical resistance and differential pressure of a gas diffusion layer for a polymer electrolyte fuel cell with respect to compression. The integrated multi-measurement system simultaneously measures changes in the physical properties of the gas diffusion layer depending on pressure upon measurement of the physical properties of the gas diffusion layer of the fuel cell and also measures through-plane permeability in which a gas is passed through a sample in a direction perpendicular to the sample and in-plane permeability in which a gas is passed through a sample in a direction parallel to the sample.