发明授权
- 专利标题： Tissue engineered tendons and ligaments
- 专利标题（中）： 组织工程肌腱和韧带
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申请号： US11351127申请日： 2006-02-09
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公开(公告)号： US07914579B2公开(公告)日： 2011-03-29
- 发明人: Charles A. Vacanti , Yi Lin Cao , Robert S. Langer , Joseph P. Vacanti , Keith Paige , Joseph Upton
- 申请人： Charles A. Vacanti , Yi Lin Cao , Robert S. Langer , Joseph P. Vacanti , Keith Paige , Joseph Upton
- 申请人地址： US MA Boston US MA Cambridge
- 专利权人： Children's Medical Center Corporation,Massachusetts Institute of Technology
- 当前专利权人： Children's Medical Center Corporation,Massachusetts Institute of Technology
- 当前专利权人地址： US MA Boston US MA Cambridge
- 代理机构： Clark & Elbing LLP
- 代理商 Kristina Bieker-Brady
- 主分类号： A61F2/08
- IPC分类号： A61F2/08 ; A61F2/42
摘要：
Connective tissue, including neo-tendons and ligaments, has been constructed using biodegradable synthetic scaffolds seeded with tenocytes. The scaffolds are preferably formed from biodegradable fibers formed of a polymer such as polyglycolic acid-polylactic acid copolymers, and seeded with cells isolated from autologous tendon or ligament by means of enzymatic digestion or direct seeding into tissue culture dishes from explants. The cell polymer constructs are then surgically transplanted to replace missing segments of functioning tendon or ligament.
公开/授权文献
- US20070005139A1 Tissue engineered tendons and ligaments 公开/授权日：2007-01-04
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