发明授权
US07915003B2 Human T2R receptors for ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators
有权
用于雷尼替丁，士的宁和denatonium的人T2R受体和用于鉴定人类苦味调节剂的相关测定法
- 专利标题： Human T2R receptors for ranitidine, strychnine and denatonium and related assays for identifying human bitter taste modulators
- 专利标题（中）： 用于雷尼替丁，士的宁和denatonium的人T2R受体和用于鉴定人类苦味调节剂的相关测定法
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申请号： US12166980申请日： 2008-07-02
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公开(公告)号： US07915003B2公开(公告)日： 2011-03-29
- 发明人: Xiaodong Li , Hong Xu , Huixian Tang , Qing Li
- 申请人： Xiaodong Li , Hong Xu , Huixian Tang , Qing Li
- 申请人地址： US CA San Diego
- 专利权人： Senomyx, Inc.
- 当前专利权人： Senomyx, Inc.
- 当前专利权人地址： US CA San Diego
- 代理机构： Hunton & Williams LLP
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; C07K14/705
摘要：
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter ligands, i.e., acetaminophen, ranitidine, strychnine and denatonium. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors and which may be used as additives in foods, beverages and medicinals for modifying (blocking) T2R-associated bitter taste.
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