发明授权
- 专利标题： Toll-like receptor 5 ligands and methods of use
- 专利标题（中）： Toll样受体5配体及使用方法
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申请号： US10125692申请日： 2002-04-17
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公开(公告)号： US07915381B2公开(公告)日： 2011-03-29
- 发明人: Alan Aderem , Fumitaka Hayashi , Kelly D. Smith , David M. Underhill , Adrian Ozinsky
- 申请人： Alan Aderem , Fumitaka Hayashi , Kelly D. Smith , David M. Underhill , Adrian Ozinsky
- 申请人地址： US WA Seattle US WA Seattle
- 专利权人： Institute for Systems Biology,University of Washington
- 当前专利权人： Institute for Systems Biology,University of Washington
- 当前专利权人地址： US WA Seattle US WA Seattle
- 代理机构： Morrison & Foerster LLP
- 主分类号： A61K48/00
- IPC分类号： A61K48/00 ; A61K39/02 ; A61K31/715 ; C12N9/00
摘要：
The invention provides an immunomodulatory flagellin peptide having at least about 10 amino acids of substantially the amino acid sequence GAVQNRFNSAIT (SEQ ID NO:2), or a modification thereof, and having toll-like receptor 5 (TLR5) binding. Methods of inducing an immune response are also provided.
公开/授权文献
- US20030044429A1 Toll-like receptor 5 ligands and methods of use 公开/授权日：2003-03-06