发明授权
US07917303B2 Method for identifying combinations of motifs that do not mutate simultaneously in a set of viral polypeptide sequences comprising a putative drug binding site
有权
用于鉴定在一组病毒多肽序列中同时突变的基序组合的方法，所述病毒多肽序列包含推定的药物结合位点
- 专利标题： Method for identifying combinations of motifs that do not mutate simultaneously in a set of viral polypeptide sequences comprising a putative drug binding site
- 专利标题（中）： 用于鉴定在一组病毒多肽序列中同时突变的基序组合的方法，所述病毒多肽序列包含推定的药物结合位点
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申请号： US11480014申请日： 2006-06-30
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公开(公告)号： US07917303B2公开(公告)日： 2011-03-29
- 发明人: Anne Vanet , Michaela Muller-Trutwin , Thomas Valère , Sophie Brouillet , Emmanuelle Ollivier , Laurent Marsan
- 申请人： Anne Vanet , Michaela Muller-Trutwin , Thomas Valère , Sophie Brouillet , Emmanuelle Ollivier , Laurent Marsan
- 申请人地址： FR
- 专利权人： Centre National de la Recherche Scientifique—CNRS
- 当前专利权人： Centre National de la Recherche Scientifique—CNRS
- 当前专利权人地址： FR
- 代理机构： DLA Piper LLP (US)
- 优先权： FR0107808 20010614
- 主分类号： G01N33/48
- IPC分类号： G01N33/48
摘要：
Methods for identifying a motif or a combination of motifs having a Boolean state of predetermined mutations in a set of sequences including a) aligning a set of sequences of ordered motifs represented by a single-character code, b) comparing a reference sequence with the set of sequences aligned in step (a), c) identifying motifs not having mutated simultaneously and/or motifs having mutated simultaneously at least once on at least one sequence of the set and not having mutated on another sequence of the set.
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