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发明授权
US07919322B2 Targeted deletions using retroelement-mediated placement of recombination sites 有权
使用逆转录介导置换重组位点的靶向缺失

Targeted deletions using retroelement-mediated placement of recombination sites
摘要：
The present invention provides methods, nucleic acid constructs, and kits for selectively deleting a region of a nucleic acid sequence. Specifically, it utilizes retargeting retroelements to place site-specific recombination sites at targeted locations in the nucleic acid sequence. The region between the recombination sites is then deleted using a site-specific recombination system.
摘要（中）：

本发明提供了用于选择性缺失核酸序列区域的方法，核酸构建体和试剂盒。 具体地，其利用重靶向逆转录酶将位点特异性重组位点置于核酸序列中的靶位点。 然后使用位点特异性重组系统删除重组位点之间的区域。

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