Invention Grant
- Patent Title: Amorphous object of cinnamide compound
- Patent Title (中): 肉桂酰胺化合物的无定形物
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Application No.: US11663550Application Date: 2005-10-25
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Publication No.: US07923563B2Publication Date: 2011-04-12
- Inventor: Ikuo Kushida , Eriko Doi , Koichi Ito
- Applicant: Ikuo Kushida , Eriko Doi , Koichi Ito
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2004-310909 20041026
- International Application: PCT/JP2005/019626 WO 20051025
- International Announcement: WO2006/046575 WO 20060504
- Main IPC: C07D401/06
- IPC: C07D401/06

Abstract:
An amorphous object of (3E)-1-[l(s)-1-(4-fluorophenyl)ethyl]-3-[3-methoxy-4-(4methyl-1H-imidazol-1-yl)benzylidene]piperidine-2-one, which is represented by the formula (1) and has Aβ-production inhibitory activity. The amorphous object has such satisfactory properties that it has excellent solubility, is stable, does not readily become a crystalline form, and has low hygroscopicity. It is hence suitable for use in pharmaceutical preparations.
Public/Granted literature
- US20090203916A1 Amorphous object of cinnamide compound Public/Granted day:2009-08-13
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