发明授权
- 专利标题： Regulation of integrin surface expression
- 专利标题（中）： 整合素表面表达调控
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申请号： US12543836申请日： 2009-08-19
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公开(公告)号： US07928084B2公开(公告)日： 2011-04-19
- 发明人: W. Beau Mitchell , Mahmoud Yazdani Abyaneh , Amanda Chen
- 申请人： W. Beau Mitchell , Mahmoud Yazdani Abyaneh , Amanda Chen
- 申请人地址： US NY New York
- 专利权人： New York Blood Center, Inc.
- 当前专利权人： New York Blood Center, Inc.
- 当前专利权人地址： US NY New York
- 代理机构： K&L Gates LLP
- 代理商 Louis C. Cullman; Michelle Glasky Bergman
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H21/04
摘要：
Disclosed are methods and compositions for preventing and treating conditions associated with platelet aggregation, comprising administering a therapeutically effective amount of a composition that modifies the interaction of DNAJC10 with αIIbβ3 in a megakaryocyte, thereby altering the expression of αIIbβ3 on the surface of the megakaryocyte.
公开/授权文献
- US20100048677A1 Regulation of Integrin Surface Expression 公开/授权日：2010-02-25
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