发明授权
- 专利标题: Sulfonyl amide derivatives for the treatment of abnormal cell growth
- 专利标题(中): 磺酰胺衍生物用于治疗异常细胞生长
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申请号: US12105151申请日: 2008-04-17
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公开(公告)号: US07928109B2公开(公告)日: 2011-04-19
- 发明人: Michael Joseph Luzzio , Kevin Daniel Freeman-Cook , Samit Kumar Bhattacharya , Matthew Merrill Hayward , Catherine Angela Hulford , Christopher Lowell Autry , Xumiao Zhao , Jun Xiao , Kendra Louise Nelson
- 申请人: Michael Joseph Luzzio , Kevin Daniel Freeman-Cook , Samit Kumar Bhattacharya , Matthew Merrill Hayward , Catherine Angela Hulford , Christopher Lowell Autry , Xumiao Zhao , Jun Xiao , Kendra Louise Nelson
- 申请人地址: US NY New York
- 专利权人: Pfizer Inc
- 当前专利权人: Pfizer Inc
- 当前专利权人地址: US NY New York
- 代理商 Jeffrey H. Tidwell; Stephen D. Prodnuk; Leslie A. Robinson
- 主分类号: C07D239/48
- IPC分类号: C07D239/48 ; C07D403/12 ; A61K31/506
摘要:
The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
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