发明授权
- 专利标题： Multistep process for the physical depolymerization of heparin and products obtained therefrom
- 专利标题（中）： 用于肝素物理解聚和由其获得的产物的多步法
-
申请号： US11279699申请日： 2006-04-13
-
公开(公告)号： US07939512B2公开(公告)日： 2011-05-10
- 发明人: Luigi De Ambrosi , Sergio Gonella , Donata Bensi , Giangiacomo Torri , Antonella Bisio , Elena Vismara
- 申请人： Luigi De Ambrosi , Sergio Gonella , Donata Bensi , Giangiacomo Torri , Antonella Bisio , Elena Vismara
- 申请人地址： IT Milan
- 专利权人： Laboratori Derivati Organici SpA
- 当前专利权人： Laboratori Derivati Organici SpA
- 当前专利权人地址： IT Milan
- 代理机构： Baker Botts L.L.P.
- 主分类号： A61K31/727
- IPC分类号： A61K31/727 ; C08B37/10
摘要：
The present invention is directed to a multistep process for the physical depolymerization of heparin wherein heparin is subjected to at least two γ-ray irradiations and wherein between two irradiation steps the depolymerised heparin is subjected to a separation step and only a fraction of the depolymerised heparin obtained from the first irradiation is subjected to the second irradiation step. It is also directed to heparin-derived oligosaccharide fractions obtainable by the process of the invention.
公开/授权文献
信息查询
IPC分类:
