Invention Grant
US07939538B2 Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
失效
用于预防和治疗炎性和免疫调节性疾病和疾病的化合物，组合物和方法
- Patent Title: Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
- Patent Title (中): 用于预防和治疗炎性和免疫调节性疾病和疾病的化合物，组合物和方法
-
Application No.: US11168005Application Date: 2005-06-27
-
Publication No.: US07939538B2Publication Date: 2011-05-10
- Inventor: Zice Fu , Michael G. Johnson , An-Rong Li , Andrew P. Marcus , Julio C. Medina , Philippe Bergeron , Xiaoqi Chen , Xiaohui Du , Jeffrey Deignan , Jason A. Duquette , Darin Gustin , Jeffrey T. Mihalic , Jiwen Liu
- Applicant: Zice Fu , Michael G. Johnson , An-Rong Li , Andrew P. Marcus , Julio C. Medina , Philippe Bergeron , Xiaoqi Chen , Xiaohui Du , Jeffrey Deignan , Jason A. Duquette , Darin Gustin , Jeffrey T. Mihalic , Jiwen Liu
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent G. Prabhakar Reddy
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D471/04 ; C07D239/90 ; C07D239/91
Abstract:
Compounds are provided having the formula: wherein variables Ra, R1, R2, R3, R4, A1, A4, L, Q, X and subscript n as described herein. The subject compounds are useful for treatment of inflammatory and immune conditions and diseases. Compositions and methods of treatment using the subject compounds are also provided. For example, the subject methods are useful for treatment of inflammatory and immune disorders and disease such as multiple sclerosis, rheumatoid arthritis, psoriasis, and inflammatory bowel disease.
Public/Granted literature
Information query
IPC分类:
