Invention Grant
- Patent Title: Oral dosage form for propiverine or its pharmaceutically acceptable salts with an extended release of the active ingredient
- Patent Title (中): 丙泊酚或其药学上可接受的盐的延长释放活性成分的口服剂型
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Application No.: US10492270Application Date: 2002-10-08
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Publication No.: US07943176B2Publication Date: 2011-05-17
- Inventor: Thomas Gramatte , Peter Gruber , Michael Heschel , Dirk Pamperin , Jan Ploen , Steffen Scheithauser , Wolfgang Wehner , Peter Guldner
- Applicant: Thomas Gramatte , Peter Gruber , Michael Heschel , Dirk Pamperin , Jan Ploen , Steffen Scheithauser , Wolfgang Wehner , Peter Guldner
- Applicant Address: DE Dresden
- Assignee: Apogepha Arzneimittel GmbH
- Current Assignee: Apogepha Arzneimittel GmbH
- Current Assignee Address: DE Dresden
- Agency: Vidas, Arrett & Steinkraus
- Priority: DE10149674 20011009
- International Application: PCT/EP02/11253 WO 20021008
- International Announcement: WO03/030869 WO 20030417
- Main IPC: A61K9/14
- IPC: A61K9/14

Abstract:
By suitable retardation oral pharmaceutical compositions containing propiverine or one or several pharmaceutically acceptable salts thereof in an amount of 4 mg to 60 mg propiverine and having a prolonged release of the active agent are produced. Preferably a blend of active agent and optionally one or more acidic substances having a pKa value of less than 6.65 are provided with a retarding coating or are embedded in a matrix which is then optionally coated with further retarding layers.
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