发明授权
- 专利标题： Non-nucleotide composition for inhibiting platelet aggregation
- 专利标题（中）： 用于抑制血小板聚集的非核苷酸组合物
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申请号： US12552465申请日： 2009-09-02
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公开(公告)号： US07943760B2公开(公告)日： 2011-05-17
- 发明人: Robert Plourde, Jr. , Sammy R. Shaver , James G. Douglass, III , Paul S. Watson , José L. Boyer , Chi Tu , Melwyn A. Abreo , Lorenzo J. Alfaro-Lopez , Yangbo Feng , Daniel F. Harvey , Tatyana V. Khasonova
- 申请人： Robert Plourde, Jr. , Sammy R. Shaver , James G. Douglass, III , Paul S. Watson , José L. Boyer , Chi Tu , Melwyn A. Abreo , Lorenzo J. Alfaro-Lopez , Yangbo Feng , Daniel F. Harvey , Tatyana V. Khasonova
- 申请人地址： US NC Durham
- 专利权人： Inspire Pharmaceuticals, Inc.
- 当前专利权人： Inspire Pharmaceuticals, Inc.
- 当前专利权人地址： US NC Durham
- 代理机构： Perkins Coie LLP
- 代理商 Viola T. Kung
- 主分类号： C07H19/16
- IPC分类号： C07H19/16 ; A01N43/04 ; A61K31/70
摘要：
This invention is directed to a method of preventing or treating diseases or conditions associated with platelet aggregation. The method is also directed to a method of treating thrombosis or related disorders. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a non-nucleotide compound, preferably a P2Y12 receptor antagonist compound, wherein said amount is effective to inhibit platelet aggregation. The compounds useful for this invention include compounds of general Formulae I and III-XII, or salts, hydrates, and solvates thereof. The present invention also provides novel compounds of Formulae I and III-XII.