发明授权
- 专利标题: Compositions and methods of tolerizing a primate to an antigen
- 专利标题(中): 将灵长类动物耐受抗原的组合物和方法
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申请号: US11486293申请日: 2006-07-13
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公开(公告)号: US07947272B2公开(公告)日: 2011-05-24
- 发明人: Mark Frewin , Herman Waldmann , Scott Gorman , Geoff Hale , Patricia Rao , Tadeusz Kornaga , Douglas Ringler , Stephen Cobbold , Dawn Winsor-Hines
- 申请人: Mark Frewin , Herman Waldmann , Scott Gorman , Geoff Hale , Patricia Rao , Tadeusz Kornaga , Douglas Ringler , Stephen Cobbold , Dawn Winsor-Hines
- 申请人地址: US MA Cambridge GB Oxford GB Cambridge
- 专利权人: Tolerx, Inc.,Isis Innovation, Ltd.,Cambridge University Technical Services, Ltd.
- 当前专利权人: Tolerx, Inc.,Isis Innovation, Ltd.,Cambridge University Technical Services, Ltd.
- 当前专利权人地址: US MA Cambridge GB Oxford GB Cambridge
- 代理商 Elliot M. Olstein; Raymond J. Lillie
- 主分类号: A61K39/395
- IPC分类号: A61K39/395
摘要:
Inducing tolerance in a primate by use of a compound, or a combination of at least two compounds, that has certain characteristics when tested in vitro. The compound, alone or in combination, is preferably TRX1 antibody and the compound or combination is preferably used in accordance with a specified dosing regimen.
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