发明授权
- 专利标题: Conjugate of an antibody against CCR5 and an antifusogenic peptide
- 专利标题(中): 抗CCR5抗体和抗融合肽的缀合物
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申请号: US11893899申请日: 2007-08-17
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公开(公告)号: US07951920B2公开(公告)日: 2011-05-31
- 发明人: Michael Brandt , Stephan Fischer , Erhard Kopetzki , Suryanarayana Sankuratri , Ralf Schumacher
- 申请人: Michael Brandt , Stephan Fischer , Erhard Kopetzki , Suryanarayana Sankuratri , Ralf Schumacher
- 申请人地址: US CA Palo Alto
- 专利权人: Roche Palo Alto LLC
- 当前专利权人: Roche Palo Alto LLC
- 当前专利权人地址: US CA Palo Alto
- 代理商 Robert C. Hall
- 优先权: EP06017156 20060817; EP06020647 20060929
- 主分类号: C07K17/00
- IPC分类号: C07K17/00 ; C07K17/14 ; C12P21/08 ; A61K39/00
摘要:
The current invention is related to a conjugate comprising one or more antifusogenic peptides and an anti-CCR5 antibody (mAb CCR5) characterized in that one to eight antifusogenic peptides are each conjugated to one terminus of the heavy and/or light chains of the anti-CCR5 antibody and to the pharmaceutical use of the conjugate.
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