In order to provide a seal arrangement for sealing between a first medium space filled with a first medium and a second medium space filled with a second medium which ensures reliable sealing between the medium spaces with very low leakage values even over a prolonged period of use, wherein said seal arrangement comprises a moveable component which is displaceable in the longitudinal direction thereof and/or rotatable about the longitudinal direction thereof and extends through the seal arrangement and wherein the seal arrangement comprises a sealing element which comprises a first sealing region that is sealing in relation to the first medium space and a second sealing region that is sealing in relation to the second medium space, wherein the first sealing region comprises a first dynamic sealing section abutting against the moveable component and the second sealing region comprises a second dynamic sealing section abutting against the moveable component and at least one of the two dynamic sealing sections has at least two sealing lips, it is proposed that each of the two sealing regions should comprise at least one respective spring element which biases the dynamic sealing section of the respective sealing region against the moveable component.